中心动态、研究进展与爪蟾科研相关信息。Center updates, research progress and Xenopus-related news.
使用本中心资源完成的代表性研究成果，含 23 篇论文与 136+ 家客户名单。Representative studies — 23 papers and 136+ client institutions.
从受精卵到自由游动蝌蚪的关键发育时期与分期方法。Key stages from fertilized egg to free-swimming tadpole.
介绍国内利用爪蟾开展研究的代表性实验室与方向。Representative labs working with Xenopus in China.
为爪蟾科研人员提供便利的资源共享平台。A convenient shared platform for the Xenopus community.
卵母细胞表达系统、核移植、卵提取物、染色质研究与 Xenbase 数据库全面综述。Comprehensive overview of oocyte expression, nuclear transplantation, egg extracts and Xenbase.
Wnt/β-catenin–SOX2 轴调控视觉经验依赖的神经干细胞稳态。Int J Mol Sci 2023。Wnt/β-catenin–SOX2 axis mediates experience-dependent NSPC homeostasis. Int J Mol Sci 2023.
前沿资讯、数据资源、资源协作、活体供应与 TEVC/卵母细胞注射等技术支持服务。Information, data, collaboration, live specimens and technical services including TEVC and oocyte injection.
约 1700 万年前两物种杂交形成异源四倍体，拥有约 50000 个基因。Nature 2016。Allotetraploid formed ~17 Mya by hybridization; ~50,000 genes. Nature 2016.
标准化养殖基地，全年稳定供应，支持卵母细胞提取、产卵诱导与毒理学研究。Year-round stable supply from standardized facility; supports oocyte extraction, spawning induction and toxicology.
AB 品系野生型斑马鱼，适用于毒理学、发育成像、神经行为学与药物筛选。AB wild-type zebrafish for toxicology, imaging, neurobehavior and drug screening.
Amphibase 项目整合 22 个两栖动物物种转录组，克服多倍体基因组注释挑战。Amphibase integrates transcriptomes of 22 amphibian species, addressing polyploid genome annotation.
BONCAT+MudPIT 揭示 CPEB 急性合成是爪蟾蝌蚪视觉学习的必要条件。Cell Rep 2014。BONCAT+MudPIT reveals CPEB synthesis as essential for Xenopus tadpole visual learning. Cell Rep 2014.
Kv1.1 过表达证明相对放电水平在竞争中指令性地驱动感受野精细化。J Neurosci 2012。Kv1.1 overexpression proves relative firing rate is instructive for competitive receptive field refinement. J Neurosci 2012.
双光子钙成像揭示视顶盖神经元在训练后发生功能性空间集群重组。PLoS Biol 2012。Two-photon imaging reveals functional cluster reorganization in the tectum after visual training. PLoS Biol 2012.
双向 E/I 失衡均损伤视觉回避，证实兴奋抑制平衡是脑功能必要条件。J Neurophysiol 2011。Bidirectional E/I disruption both impair visual avoidance, confirming E/I balance is essential. J Neurophysiol 2011.
从 Hogben 妊娠试验到 Gurdon 核移植，爪蟾在生物学研究中的辉煌历程综述。From Hogben's pregnancy test to Gurdon's nuclear transplantation — a historical overview.
形态、习性、繁殖、饲养与入侵物种警示，1991 年经典科普文章。Morphology, behavior, reproduction, husbandry and invasive species warning — a 1991 classic.