首页Home / 技术服务Services / 早期胚胎单细胞Single-cell

非洲爪蟾早期胚胎单细胞提取Early-embryo single-cell isolation

在显微操作下分离爪蟾早期胚胎的特定卵裂球（blastomere），用于细胞谱系追踪、母源决定子研究、发育信号分析与单细胞测序，保证细胞活性与定位准确。Micromanipulation-based isolation of specific blastomeres from early Xenopus embryos — for lineage tracing, maternal-determinant studies, developmental signaling and single-cell sequencing.

爪蟾早期胚胎/卵母细胞

应用方向Applications

  • 特定卵裂球分离与命运（fate）研究Blastomere isolation & cell-fate studies
  • 母源决定子与背腹轴建立机制Maternal determinants & axis formation
  • 发育信号通路（Wnt/β-catenin 等）Developmental signaling (Wnt/β-catenin)
  • 单细胞测序与谱系追踪取材Sampling for single-cell sequencing & lineage tracing
代表性成果Selected publications

客户使用本服务发表的论文（节选）Client papers using this service

完整名单见 客户 SCI 论文精选。Full list: client SCI papers.

EMBO Reports2021
Lysosomal degradation of the maternal dorsal determinant Hwa
Zhu et al. · EMBO Rep · 母源背部决定子 HwaMaternal dorsal determinant
DOI
J Cell Biology2021
Phase separation of Axin organizes the β-catenin destruction complex
Nong et al. · J Cell Biol 220(4):e202012112 · Wnt / β-catenin 信号Wnt / β-catenin signaling
DOI
Cell Research2020
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex
Huang et al. · Cell Res 30(6):520–531 · 核孔复合体结构Nuclear pore complex
DOI

需要单细胞 / 卵裂球取材？Need blastomere sampling?

告诉我们目标发育时期与细胞，我们完成显微分离与交付。Tell us the stage and target cell — we handle micro-isolation and delivery.

咨询此服务Enquire